Is it safe to Take 5-HTP supplement With Melatonin?

Both 5-HTP and Melatonin can be used to improve sleep. They works differently but have similar result. Taking these two substances together may produce unintended consequences. But is it totally safe to Take 5-HTP supplement With Melatonin? Here we discuss about that briefly.

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About 5-HTP

5-HTP can not straight be used by human physique. Its benefits come alternatively in the substances your body produces with it. Serotonin is actually a neurotransmitter essential for gastrointestinal, nervous method, cardiovascular, skeletal and psychological overall health. 5-HTP supplements are often used as sleep aids, however it is serotonin that has the antidepressant, mood elevating and anti-anxiety effects that make sleep possible. Really tiny 5-HTP comes in the foods you consume. Alternatively, the body produces 5-HTP in the tryptophan discovered in protein-rich foods like eggs, meat, fish and dairy items.

About Melatonin

Melatonin can be a naturally occurring substance that aids regulate your body’s sleep-wake cycle. Most melatonin is produced and released by the pineal gland, situated inside the brain. Melatonin synthesis starts using the amino acid L-tryptophan. Initially, L-tryptophan is converted into 5-HTP. Next, 5-HTP is converted to serotonin, that is then metabolized additional to make melatonin. Melatonin will not function like the neurotransmitter serotonin; as an alternative, it triggers the sleep cycle by interacting with its personal receptors inside the brain.

5-HTP supplement With Melatonin

Is it safe to use Melatonin and 5-HTP together?

According to a research, there is almost no harmful interactions between melatonin and 5-HTP. But as 5-HTP will be converted to serotonin in the body, so we also need to discuss about the interaction of melatonin with serotonin. While serotonin is needed for melatonin production, supplemental 5-HTP does not directly increase melatonin levels. The conversion of serotonin to melatonin can be reversed. Increased serotonin from supplemental 5-HTP and melatonin may lead to serotonin syndrome, a potentially life threating condition caused by high serotonin levels. Symptoms of serotonin syndrome include agitation, diarrhea, fast heart beat, hallucinations, loss of coordination and changes in blood pressure.

In order to avoid the risks, we suggest you to consult your physician always if your want to take Melatonin and 5-HTP together or combine any dietary supplements.